Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRAF6	HGNC:12036 (HGNC) 7189 (Entrez Gene) 602355 (OMIM) TRAF6 (Alliance of Genome Resources)	Chr11 p12	Chr11:36483769-36510272 (-) GRCh38		Q9Y4K3 (UniProt | EBI) NM_145803 (RefSeq)
mouse	Traf6	MGI:108072 (MGI) 22034 (Entrez Gene) Gene Tree Traf6 (Alliance of Genome Resources)	Chr2 53.9 cM	Chr2:101508774-101532014 (+) GRCm39	hypohidrotic ectodermal dysplasia	ENSMUSG00000027164 (Ensembl Gene Model) ENSMUSP00000004949 (Ensembl) ENSMUST00000004949 (Ensembl)
rat	Traf6	RGD:1306853 (Rat Genome Database) 311245 (Entrez Gene) Traf6 (Alliance of Genome Resources)	Chr3 q31			B5DF45 (UniProt | EBI) NM_001107754 (RefSeq)
zebrafish	traf6	ZDB-GENE-030131-5735 (Zebrafish Model Organism Database) 554561 (Entrez Gene) traf6 (Alliance of Genome Resources)	Chr7			Q6IWL4 (UniProt | EBI) NM_001044752 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.