Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTMA	HGNC:9623 (HGNC) 5757 (Entrez Gene) 188390 (OMIM) PTMA (Alliance of Genome Resources)	Chr2 q37.1	Chr2:231706895-231713551 (+) GRCh38		P06454 (UniProt | EBI) NM_001099285 (RefSeq)
mouse	Ptma	MGI:97803 (MGI) 19231 (Entrez Gene) Gene Tree Ptma (Alliance of Genome Resources)	Chr1 43.96 cM	Chr1:86454448-86458434 (+) GRCm39	polycystic kidney disease pulmonary emphysema	ENSMUSG00000026238 (Ensembl Gene Model) ENSMUSP00000140270 (Ensembl) ENSMUST00000188699 (Ensembl)
rat	Ptma	RGD:61829 (Rat Genome Database) 29222 (Entrez Gene) Ptma (Alliance of Genome Resources)	Chr9 q35			P06302 (UniProt | EBI) NM_021740 (RefSeq)
	Ptmal3	RGD:1596138 (Rat Genome Database) 689166 (Entrez Gene) Ptmal3 (Alliance of Genome Resources)	Chr18 q13			XP_038953225 (RefSeq)
	Ptmal5	RGD:2323611 (Rat Genome Database) 100359583 (Entrez Gene) Ptmal5 (Alliance of Genome Resources)	Chr13
zebrafish	ptmaa	ZDB-GENE-030131-7647 (Zebrafish Model Organism Database) 335707 (Entrez Gene) ptmaa (Alliance of Genome Resources)	Chr6			Q6NV32 (UniProt | EBI) NM_194376 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.