Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRG4	HGNC:9364 (HGNC) 10216 (Entrez Gene) 604283 (OMIM) PRG4 (Alliance of Genome Resources)	Chr1 q31.1	Chr1:186296273-186314567 (+) GRCh38	camptodactyly-arthropathy-coxa vara-pericarditis syndrome pericarditis	Q92954 (UniProt | EBI) NM_001303232 (RefSeq)
mouse	Prg4	MGI:1891344 (MGI) 96875 (Entrez Gene) Gene Tree Prg4 (Alliance of Genome Resources)	Chr1 63.84 cM	Chr1:150325163-150341916 (-) GRCm39		96875 (NCBI Gene Model) Q9JM99 (UniProt | EBI) NM_021400 (RefSeq)
rat	Prg4	RGD:1308976 (Rat Genome Database) 289104 (Entrez Gene) Prg4 (Alliance of Genome Resources)	Chr13 q21			NP_001099432 (RefSeq) NM_001105962 (RefSeq)
zebrafish	prg4a	ZDB-GENE-030131-8295 (Zebrafish Model Organism Database) 336351 (Entrez Gene) prg4a (Alliance of Genome Resources)	Chr2			NP_997918 (RefSeq) NM_212753 (RefSeq)
	prg4b	ZDB-GENE-041014-324 (Zebrafish Model Organism Database) 553377 (Entrez Gene) prg4b (Alliance of Genome Resources)	Chr20			NP_001315259 (RefSeq) NM_001037673 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.