Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CES2	HGNC:1864 (HGNC) 8824 (Entrez Gene) 605278 (OMIM) CES2 (Alliance of Genome Resources)	Chr16 q22.1	Chr16:66934444-66945096 (+) GRCh38		O00748 (UniProt | EBI) NM_003869 (RefSeq)
mouse	Ces2a	MGI:2142491 (MGI) 102022 (Entrez Gene) Gene Tree Ces2a (Alliance of Genome Resources)	Chr8 53.04 cM	Chr8:105460635-105468266 (+) GRCm39		102022 (NCBI Gene Model) Q8QZR3 (UniProt | EBI) NM_133960 (RefSeq)
rat	Ces2a	RGD:708353 (Rat Genome Database) 246252 (Entrez Gene) Ces2a (Alliance of Genome Resources)	Chr19 p14			Q8K3R0 (UniProt | EBI) NM_144743 (RefSeq)
	Ces2i	RGD:1565045 (Rat Genome Database) 292152 (Entrez Gene) Ces2i (Alliance of Genome Resources)	Chr1 q55			XP_038952723 (RefSeq)
	Ces2j	RGD:1591368 (Rat Genome Database) 685645 (Entrez Gene) Ces2j (Alliance of Genome Resources)	Chr19 p14			NP_001177309 (RefSeq) NM_001190380 (RefSeq)
zebrafish	ces3	ZDB-GENE-030131-9563 (Zebrafish Model Organism Database) 560651 (Entrez Gene) ces3 (Alliance of Genome Resources)	Chr18			NP_001038401 (RefSeq) NM_001044936 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.