Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE4B	HGNC:8781 (HGNC) 5142 (Entrez Gene) 600127 (OMIM) PDE4B (Alliance of Genome Resources)	Chr1 p31.3	Chr1:65792510-66374579 (+) GRCh38	alcohol dependence	Q07343 (UniProt | EBI) NM_001037340 (RefSeq)
mouse	Pde4b	MGI:99557 (MGI) 18578 (Entrez Gene) Gene Tree Pde4b (Alliance of Genome Resources)	Chr4 46.99 cM	Chr4:101944740-102464456 (+) GRCm39		ENSMUSG00000028525 (Ensembl Gene Model) ENSMUSP00000102524 (Ensembl) ENSMUST00000106911 (Ensembl)
rat	Pde4b	RGD:3280 (Rat Genome Database) 24626 (Entrez Gene) Pde4b (Alliance of Genome Resources)	Chr5 q33			P14646 (UniProt | EBI) NM_001398935 (RefSeq)
zebrafish	pde4ba	ZDB-GENE-030131-9570 (Zebrafish Model Organism Database) 565706 (Entrez Gene) pde4ba (Alliance of Genome Resources)	Chr6			XP_068074429 (RefSeq)
	pde4bb	ZDB-GENE-070912-454 (Zebrafish Model Organism Database) 555599 (Entrez Gene) pde4bb (Alliance of Genome Resources)	Chr2			XP_009296520 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.