Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HLA-DRA	HGNC:4947 (HGNC) 3122 (Entrez Gene) 142860 (OMIM) HLA-DRA (Alliance of Genome Resources)	Chr6 p21.32	Chr6:32439878-32445046 (+) GRCh38	allergic disease asthma autoimmune thyroiditis late onset Parkinson's disease multiple sclerosis Parkinson's disease	P01903 (UniProt | EBI) NM_019111 (RefSeq)
mouse	H2-Ea	MGI:95900 (MGI) 100504404 (Entrez Gene) Gene Tree H2-Ea (Alliance of Genome Resources)	Chr17 17.98 cM	Chr17:34560926-34563618 (-) GRCm39		ENSMUSG00000036322 (Ensembl Gene Model) ENSMUSP00000158275 (Ensembl) ENSMUST00000134042 (Ensembl)
rat	RT1-Da	RGD:1593283 (Rat Genome Database) 294269 (Entrez Gene) RT1-Da (Alliance of Genome Resources)	Chr20 p12			NP_001008847 (RefSeq) NM_001008847 (RefSeq)
zebrafish	mhc2d8.35a1	ZDB-GENE-131121-38 (Zebrafish Model Organism Database) 795595 (Entrez Gene) mhc2d8.35a1 (Alliance of Genome Resources)	Chr8			XP_009302401 (RefSeq)
	mhc2d8.37a1	ZDB-GENE-091204-401 (Zebrafish Model Organism Database) 103908641 (Entrez Gene) mhc2d8.37a1 (Alliance of Genome Resources)	Chr8			XP_005167290 (RefSeq)
	mhc2d8.46a	ZDB-GENE-081105-52 (Zebrafish Model Organism Database) 571282 (Entrez Gene) mhc2d8.46a (Alliance of Genome Resources)	Chr8			XP_699949 (RefSeq)
	mhc2dga	ZDB-GENE-030616-505 (Zebrafish Model Organism Database) 368614 (Entrez Gene) mhc2dga (Alliance of Genome Resources)	Chr8			NP_001007206 (RefSeq) NM_001007205 (RefSeq)
	si:busm1-194e12.8	ZDB-GENE-030616-323 (Zebrafish Model Organism Database) 368816 (Entrez Gene) si:busm1-194e12.8 (Alliance of Genome Resources)	Chr8			NP_001007430 (RefSeq) NM_001007429 (RefSeq)
	zgc:123107	ZDB-GENE-051113-192 (Zebrafish Model Organism Database) 641415 (Entrez Gene) zgc:123107 (Alliance of Genome Resources)	Chr4			NP_001077290 (RefSeq) NM_001037404 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.