Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRIO	HGNC:12303 (HGNC) 7204 (Entrez Gene) 601893 (OMIM) TRIO (Alliance of Genome Resources)	Chr5 p15.2	Chr5:14143342-14532128 (+) GRCh38	autosomal dominant intellectual developmental disorder autosomal dominant intellectual developmental disorder 44	O75962 (UniProt | EBI) NM_007118 (RefSeq)
mouse	Trio	MGI:1927230 (MGI) 223435 (Entrez Gene) Gene Tree Trio (Alliance of Genome Resources)	Chr15 10.4 cM	Chr15:27730737-28025934 (-) GRCm39		ENSMUSG00000022263 (Ensembl Gene Model) ENSMUSP00000087714 (Ensembl) ENSMUST00000090247 (Ensembl)
rat	Trio	RGD:1308360 (Rat Genome Database) 310192 (Entrez Gene) Trio (Alliance of Genome Resources)	Chr2 q22			F1M0Z1 (UniProt | EBI) NM_001107658 (RefSeq)
zebrafish	trioa	ZDB-GENE-060503-334 (Zebrafish Model Organism Database) 557667 (Entrez Gene) trioa (Alliance of Genome Resources)	Chr19			Q1LUA6 (UniProt | EBI) NM_001104526 (RefSeq)
	triob	ZDB-GENE-030616-399 (Zebrafish Model Organism Database) 368847 (Entrez Gene) triob (Alliance of Genome Resources)	Chr16			XP_068070192 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.