Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IHH	HGNC:5956 (HGNC) 3549 (Entrez Gene) 600726 (OMIM) IHH (Alliance of Genome Resources)	Chr2 q35	Chr2:219054424-219060921 (-) GRCh38	acrocapitofemoral dysplasia brachydactyly type A1 retinopathy of prematurity syndactyly type 1	Q14623 (UniProt | EBI) NM_002181 (RefSeq)
mouse	Ihh	MGI:96533 (MGI) 16147 (Entrez Gene) Gene Tree Ihh (Alliance of Genome Resources)	Chr1 38.55 cM	Chr1:74984474-74990831 (-) GRCm39	annular pancreas brachydactyly type A1 Hirschsprung's disease	16147 (NCBI Gene Model) P97812 (UniProt | EBI) NM_010544 (RefSeq)
rat	Ihh	RGD:620021 (Rat Genome Database) 84399 (Entrez Gene) Ihh (Alliance of Genome Resources)	Chr9 q33			NP_445836 (RefSeq) NM_053384 (RefSeq)
zebrafish	ihha	ZDB-GENE-051010-1 (Zebrafish Model Organism Database) 619520 (Entrez Gene) ihha (Alliance of Genome Resources)	Chr9			NP_001030165 (RefSeq) NM_001034993 (RefSeq)
	ihhb	ZDB-GENE-980526-135 (Zebrafish Model Organism Database) 30299 (Entrez Gene) ihhb (Alliance of Genome Resources)	Chr6			Q98862 (UniProt | EBI) NM_131088 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.