Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EGR2	HGNC:3239 (HGNC) 1959 (Entrez Gene) 129010 (OMIM) EGR2 (Alliance of Genome Resources)	Chr10 q21.3	Chr10:62811996-62819167 (-) GRCh38	Charcot-Marie-Tooth disease type 1D Charcot-Marie-Tooth disease type 3 Charcot-Marie-Tooth disease type 4E motor peripheral neuropathy	P11161 (UniProt | EBI) NM_001136178 (RefSeq)
mouse	Egr2	MGI:95296 (MGI) 13654 (Entrez Gene) Gene Tree Egr2 (Alliance of Genome Resources)	Chr10 34.96 cM	Chr10:67371305-67378018 (+) GRCm39	Charcot-Marie-Tooth disease type 4E	ENSMUSG00000037868 (Ensembl Gene Model) ENSMUSP00000041053 (Ensembl) ENSMUST00000048289 (Ensembl)
rat	Egr2	RGD:621608 (Rat Genome Database) 114090 (Entrez Gene) Egr2 (Alliance of Genome Resources)	Chr20 p11			P51774 (UniProt | EBI) NM_053633 (RefSeq)
zebrafish	egr2a	ZDB-GENE-030723-6 (Zebrafish Model Organism Database) 368241 (Entrez Gene) egr2a (Alliance of Genome Resources)	Chr17			NP_001315333 (RefSeq) NM_183341 (RefSeq)
	egr2b	ZDB-GENE-980526-283 (Zebrafish Model Organism Database) 30190 (Entrez Gene) egr2b (Alliance of Genome Resources)	Chr12			Q05159 (UniProt | EBI) NM_130997 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.