Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GREM2	HGNC:17655 (HGNC) 64388 (Entrez Gene) 608832 (OMIM) GREM2 (Alliance of Genome Resources)	Chr1 q43	Chr1:240489573-240612155 (-) GRCh38	tooth agenesis	Q9H772 (UniProt | EBI) NM_022469 (RefSeq)
mouse	Grem2	MGI:1344367 (MGI) 23893 (Entrez Gene) Gene Tree Grem2 (Alliance of Genome Resources)	Chr1 81.08 cM	Chr1:174661352-174749386 (-) GRCm39		23893 (NCBI Gene Model) O88273 (UniProt | EBI) NM_001421484 (RefSeq)
rat	Grem2	RGD:1560008 (Rat Genome Database) 289264 (Entrez Gene) Grem2 (Alliance of Genome Resources)	Chr13 q24			NP_001099444 (RefSeq) NM_001105974 (RefSeq)
zebrafish	grem2a	ZDB-GENE-131127-498 (Zebrafish Model Organism Database) 100002201 (Entrez Gene) grem2a (Alliance of Genome Resources)	Chr17			XP_021328765 (RefSeq)
	grem2b	ZDB-GENE-030911-9 (Zebrafish Model Organism Database) 550399 (Entrez Gene) grem2b (Alliance of Genome Resources)	Chr12			NP_001017704 (RefSeq) NM_001017704 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.