Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MBD4	HGNC:6919 (HGNC) 8930 (Entrez Gene) 603574 (OMIM) MBD4 (Alliance of Genome Resources)	Chr3 q21.3	Chr3:129430947-129440179 (-) GRCh38	colorectal carcinoma esophagus squamous cell carcinoma lung cancer rheumatoid arthritis uveal melanoma	O95243 (UniProt | EBI) NM_001276270 (RefSeq)
mouse	Mbd4	MGI:1333850 (MGI) 17193 (Entrez Gene) Gene Tree Mbd4 (Alliance of Genome Resources)	Chr6 53.72 cM	Chr6:115817658-115830332 (-) GRCm39		ENSMUSG00000030322 (Ensembl Gene Model) ENSMUSP00000032469 (Ensembl) ENSMUST00000032469 (Ensembl)
rat	Mbd4	RGD:1585874 (Rat Genome Database) 680915 (Entrez Gene) Mbd4 (Alliance of Genome Resources)	Chr4 q42			NP_001414177 (RefSeq) NM_001427248 (RefSeq)
zebrafish	mbd4	ZDB-GENE-040213-1 (Zebrafish Model Organism Database) 101887128 (Entrez Gene) mbd4 (Alliance of Genome Resources)	Chr8			XP_017213059 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.