Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF4E	HGNC:3287 (HGNC) 1977 (Entrez Gene) 133440 (OMIM) EIF4E (Alliance of Genome Resources)	Chr4 q23	Chr4:98879276-98929133 (-) GRCh38	autistic disorder	P06730 (UniProt | EBI) NM_001331017 (RefSeq)
mouse	Eif4e	MGI:95305 (MGI) 13684 (Entrez Gene) Gene Tree Eif4e (Alliance of Genome Resources)	Chr3 64.3 cM	Chr3:138231952-138265457 (+) GRCm39	autism spectrum disorder	13684 (NCBI Gene Model) P63073 (UniProt | EBI) NM_001313980 (RefSeq)
rat	Eif4e	RGD:69647 (Rat Genome Database) 117045 (Entrez Gene) Eif4e (Alliance of Genome Resources)	Chr2 q44			P63074 (UniProt | EBI) NM_053974 (RefSeq)
zebrafish	eif4ea	ZDB-GENE-040413-1 (Zebrafish Model Organism Database) 79380 (Entrez Gene) eif4ea (Alliance of Genome Resources)	Chr14			Q9DFS6 (UniProt | EBI) NM_131733 (RefSeq)
	eif4eb	ZDB-GENE-041121-14 (Zebrafish Model Organism Database) 493617 (Entrez Gene) eif4eb (Alliance of Genome Resources)	Chr13			NP_001007778 (RefSeq) NM_001007777 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.