Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RNF170	HGNC:25358 (HGNC) 81790 (Entrez Gene) 614649 (OMIM) RNF170 (Alliance of Genome Resources)	Chr8 p11.21	Chr8:42849637-42897299 (-) GRCh38	autosomal dominant sensory ataxia 1 hereditary spastic paraplegia 85	Q96K19 (UniProt | EBI) NM_001160225 (RefSeq)
mouse	Rnf170	MGI:1924983 (MGI) 77733 (Entrez Gene) Gene Tree Rnf170 (Alliance of Genome Resources)	Chr8 14.38 cM	Chr8:26609396-26633903 (+) GRCm39	hereditary ataxia	77733 (NCBI Gene Model) Q8CBG9 (UniProt | EBI) NM_001357294 (RefSeq)
rat	Rnf170	RGD:1590842 (Rat Genome Database) 364654 (Entrez Gene) Rnf170 (Alliance of Genome Resources)	Chr16			NP_001386189 (RefSeq) NM_001399260 (RefSeq)
zebrafish	rnf170	ZDB-GENE-040426-2572 (Zebrafish Model Organism Database) 406612 (Entrez Gene) rnf170 (Alliance of Genome Resources)	Chr5			Q7SZN2 (UniProt | EBI) NM_214750 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.