Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLEKHA1	HGNC:14335 (HGNC) 59338 (Entrez Gene) 607772 (OMIM) PLEKHA1 (Alliance of Genome Resources)	Chr10 q26.13	Chr10:122374696-122442600 (+) GRCh38		Q9HB21 (UniProt | EBI) NM_001377240 (RefSeq)
mouse	Plekha1	MGI:2442213 (MGI) 101476 (Entrez Gene) Gene Tree Plekha1 (Alliance of Genome Resources)	Chr7 73.19 cM	Chr7:130467486-130515042 (+) GRCm39		ENSMUSG00000040268 (Ensembl Gene Model) ENSMUSP00000074675 (Ensembl) ENSMUST00000075181 (Ensembl)
rat	Plekha1	RGD:1564153 (Rat Genome Database) 361659 (Entrez Gene) Plekha1 (Alliance of Genome Resources)	Chr1 q41			NP_001402909 (RefSeq) NM_001415980 (RefSeq)
zebrafish	plekha1a	ZDB-GENE-040426-2780 (Zebrafish Model Organism Database) 406745 (Entrez Gene) plekha1a (Alliance of Genome Resources)	Chr17			NP_998601 (RefSeq) NM_213436 (RefSeq)
	plekha1b	ZDB-GENE-110408-54 (Zebrafish Model Organism Database) 100537419 (Entrez Gene) plekha1b (Alliance of Genome Resources)	Chr12			XP_068080834 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.