Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KRT10	HGNC:6413 (HGNC) 3858 (Entrez Gene) 148080 (OMIM) KRT10 (Alliance of Genome Resources)	Chr17 q21.2	Chr17:40818117-40822614 (-) GRCh38	epidermolytic hyperkeratosis epidermolytic hyperkeratosis 2	P13645 (UniProt | EBI) NM_000421 (RefSeq)
mouse	Krt10	MGI:96685 (MGI) 16661 (Entrez Gene) Gene Tree Krt10 (Alliance of Genome Resources)	Chr11 62.92 cM	Chr11:99276080-99280190 (-) GRCm39	epidermolytic hyperkeratosis	ENSMUSG00000019761 (Ensembl Gene Model) ENSMUSP00000099420 (Ensembl) ENSMUST00000103131 (Ensembl)
rat	Krt10	RGD:1359092 (Rat Genome Database) 450225 (Entrez Gene) Krt10 (Alliance of Genome Resources)	Chr10 q31			Q6IFW6 (UniProt | EBI) NM_001413356 (RefSeq)
zebrafish	cyt1	ZDB-GENE-991008-6 (Zebrafish Model Organism Database) 30327 (Entrez Gene) cyt1 (Alliance of Genome Resources)	Chr19			NP_571182 (RefSeq) NM_131107 (RefSeq)
	cyt1l	ZDB-GENE-061026-4 (Zebrafish Model Organism Database) 792062 (Entrez Gene) cyt1l (Alliance of Genome Resources)	Chr19			NP_001076351 (RefSeq) NM_001082882 (RefSeq)
	krt1-19d	ZDB-GENE-060316-1 (Zebrafish Model Organism Database) 664718 (Entrez Gene) krt1-19d (Alliance of Genome Resources)	Chr19			XP_001342789 (RefSeq)
	krt1-19e	ZDB-GENE-050506-95 (Zebrafish Model Organism Database) 553371 (Entrez Gene) krt1-19e (Alliance of Genome Resources)	Chr19			NP_001107814 (RefSeq) NM_001114342 (RefSeq)
	krt15	ZDB-GENE-040426-2931 (Zebrafish Model Organism Database) 406844 (Entrez Gene) krt15 (Alliance of Genome Resources)	Chr11			NP_998688 (RefSeq) NM_213523 (RefSeq)
	krt17	ZDB-GENE-060503-86 (Zebrafish Model Organism Database) 100034647 (Entrez Gene) krt17 (Alliance of Genome Resources)	Chr19			NP_001076574 (RefSeq) NM_001083105 (RefSeq)
	krt91	ZDB-GENE-040801-181 (Zebrafish Model Organism Database) 445051 (Entrez Gene) krt91 (Alliance of Genome Resources)	Chr19			NP_001003445 (RefSeq) NM_001003445 (RefSeq)
	krt92	ZDB-GENE-050417-363 (Zebrafish Model Organism Database) 550522 (Entrez Gene) krt92 (Alliance of Genome Resources)	Chr19			NP_001017824 (RefSeq) NM_001017824 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.