Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CREB1	HGNC:2345 (HGNC) 1385 (Entrez Gene) 123810 (OMIM) CREB1 (Alliance of Genome Resources)	Chr2 q33.3	Chr2:207529737-207605988 (+) GRCh38	alcohol dependence heroin dependence Parkinson's disease	P16220 (UniProt | EBI) NM_004379 (RefSeq)
mouse	Creb1	MGI:88494 (MGI) 12912 (Entrez Gene) Gene Tree Creb1 (Alliance of Genome Resources)	Chr1 32.74 cM	Chr1:64571963-64643707 (+) GRCm39		12912 (NCBI Gene Model) Q01147 (UniProt | EBI) NM_009952 (RefSeq)
rat	Creb1	RGD:620218 (Rat Genome Database) 81646 (Entrez Gene) Creb1 (Alliance of Genome Resources)	Chr9 q32			P15337 (UniProt | EBI) NM_031017 (RefSeq)
zebrafish	creb1a	ZDB-GENE-040426-750 (Zebrafish Model Organism Database) 573207 (Entrez Gene) creb1a (Alliance of Genome Resources)	Chr1			NP_957203 (RefSeq) NM_200909 (RefSeq)
	creb1b	ZDB-GENE-050417-355 (Zebrafish Model Organism Database) 550516 (Entrez Gene) creb1b (Alliance of Genome Resources)	Chr9			NP_001017818 (RefSeq) NM_001017818 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.