Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DGUOK	HGNC:2858 (HGNC) 1716 (Entrez Gene) 601465 (OMIM) DGUOK (Alliance of Genome Resources)	Chr2 p13.1	Chr2:73926826-73958961 (+) GRCh38	autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 4 mitochondrial DNA depletion syndrome 3 mitochondrial metabolism disease	Q16854 (UniProt | EBI) NM_001318863 (RefSeq)
mouse	Dguok	MGI:1351602 (MGI) 27369 (Entrez Gene) Gene Tree Dguok (Alliance of Genome Resources)	Chr6 35.94 cM	Chr6:83457199-83483887 (-) GRCm39		27369 (NCBI Gene Model) Q9QX60 (UniProt | EBI) NR_177096 (RefSeq)
rat	Dguok	RGD:1304799 (Rat Genome Database) 297389 (Entrez Gene) Dguok (Alliance of Genome Resources)	Chr4 q34			NP_001100072 (RefSeq) NM_001106602 (RefSeq)
zebrafish	dguok	ZDB-GENE-040625-14 (Zebrafish Model Organism Database) 100005067 (Entrez Gene) dguok (Alliance of Genome Resources)	Chr5			NP_001093561 (RefSeq) NM_001100091 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.