Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IFNG	HGNC:5438 (HGNC) 3458 (Entrez Gene) 147570 (OMIM) IFNG (Alliance of Genome Resources)	Chr12 q15	Chr12:68154768-68159740 (-) GRCh38	acute lymphoblastic leukemia aplastic anemia ataxia telangiectasia breast cancer chronic granulomatous disease diabetic neuropathy eczema herpeticum factor VIII deficiency glucosephosphate dehydrogenase deficiency graft-versus-host disease Graves' disease hepatitis C human immunodeficiency virus infectious disease immunodeficiency 69 liver cirrhosis lupus nephritis multiple sclerosis myeloid leukemia rheumatoid arthritis sensorineural hearing loss severe acute respiratory syndrome systemic scleroderma temporal arteritis tuberculosis tuberous sclerosis 2 type 2 diabetes mellitus vesicoureteral reflux vitiligo	P01579 (UniProt | EBI) NM_000619 (RefSeq)
mouse	Ifng	MGI:107656 (MGI) 15978 (Entrez Gene) Gene Tree Ifng (Alliance of Genome Resources)	Chr10 66.75 cM	Chr10:118276951-118281797 (+) GRCm39	aplastic anemia cardiomyopathy hepatitis malaria medulloblastoma type 1 diabetes mellitus	ENSMUSG00000055170 (Ensembl Gene Model) ENSMUSP00000063800 (Ensembl) ENSMUST00000068592 (Ensembl)
rat	Ifng	RGD:2866 (Rat Genome Database) 25712 (Entrez Gene) Ifng (Alliance of Genome Resources)	Chr7 q22			P01581 (UniProt | EBI) NM_138880 (RefSeq)
zebrafish	ifng1	ZDB-GENE-040629-1 (Zebrafish Model Organism Database) 405790 (Entrez Gene) ifng1 (Alliance of Genome Resources)	Chr4			NP_998029 (RefSeq) NM_212864 (RefSeq)
	ifng1r	ZDB-GENE-060210-1 (Zebrafish Model Organism Database) 553965 (Entrez Gene) ifng1r (Alliance of Genome Resources)	Chr4			NP_001018629 (RefSeq) NM_001020793 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.