Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL1B	HGNC:5992 (HGNC) 3553 (Entrez Gene) 147720 (OMIM) IL1B (Alliance of Genome Resources)	Chr2 q14.1	Chr2:112829751-112836816 (-) GRCh38	agranulocytosis Alzheimer's disease arteriosclerosis asthma bacterial pneumonia breast cancer cervical cancer cervix uteri carcinoma in situ chronic kidney disease chronic obstructive pulmonary disease cystic fibrosis dental caries dry eye syndrome eye disease Graves' disease hepatocellular carcinoma IgA glomerulonephritis keratoconus lung disease lung non-small cell carcinoma metabolic dysfunction-associated steatotic liver disease multiple myeloma multiple sclerosis nephrotic syndrome pancreatic cancer Parkinson's disease pleural tuberculosis pulmonary tuberculosis rhinitis stomach cancer systemic lupus erythematosus systemic scleroderma thrombocytopenia thrombocytosis type 1 diabetes mellitus type 2 diabetes mellitus uveitis	P01584 (UniProt | EBI) NM_000576 (RefSeq)
mouse	Il1b	MGI:96543 (MGI) 16176 (Entrez Gene) Gene Tree Il1b (Alliance of Genome Resources)	Chr2 62.97 cM	Chr2:129206490-129213059 (-) GRCm39		16176 (NCBI Gene Model) P10749 (UniProt | EBI) NM_008361 (RefSeq)
rat	Il1b	RGD:2891 (Rat Genome Database) 24494 (Entrez Gene) Il1b (Alliance of Genome Resources)	Chr3 q36			Q63264 (UniProt | EBI) NM_031512 (RefSeq)
zebrafish	il1b	ZDB-GENE-040702-2 (Zebrafish Model Organism Database) 405770 (Entrez Gene) il1b (Alliance of Genome Resources)	Chr10			NP_998009 (RefSeq) NM_212844 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.