Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SYK	HGNC:11491 (HGNC) 6850 (Entrez Gene) 600085 (OMIM) SYK (Alliance of Genome Resources)	Chr9 q22.2	Chr9:90801600-90898549 (+) GRCh38	primary immunodeficiency disease	P43405 (UniProt | EBI) NM_003177 (RefSeq)
mouse	Syk	MGI:99515 (MGI) 20963 (Entrez Gene) Gene Tree Syk (Alliance of Genome Resources)	Chr13 27.41 cM	Chr13:52737209-52802828 (+) GRCm39		ENSMUSG00000021457 (Ensembl Gene Model) ENSMUSP00000060828 (Ensembl) ENSMUST00000055087 (Ensembl)
rat	Syk	RGD:3796 (Rat Genome Database) 25155 (Entrez Gene) Syk (Alliance of Genome Resources)	Chr17 p14			Q64725 (UniProt | EBI) NM_012758 (RefSeq)
zebrafish	syk	ZDB-GENE-040702-3 (Zebrafish Model Organism Database) 405769 (Entrez Gene) syk (Alliance of Genome Resources)	Chr10			NP_998008 (RefSeq) NM_212843 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.