Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRSS8	HGNC:9491 (HGNC) 5652 (Entrez Gene) 600823 (OMIM) PRSS8 (Alliance of Genome Resources)	Chr16 p11.2	Chr16:31131433-31135727 (-) GRCh38		Q16651 (UniProt | EBI) NM_002773 (RefSeq)
mouse	Prss8	MGI:1923810 (MGI) 76560 (Entrez Gene) Gene Tree Prss8 (Alliance of Genome Resources)	Chr7 69.84 cM	Chr7:127524889-127529266 (-) GRCm39	autosomal recessive congenital ichthyosis 4B	76560 (NCBI Gene Model) Q9ESD1 (UniProt | EBI) NM_133351 (RefSeq)
rat	Prss8	RGD:619973 (Rat Genome Database) 192107 (Entrez Gene) Prss8 (Alliance of Genome Resources)	Chr1 q37			Q9ES87 (UniProt | EBI) NM_138836 (RefSeq)
zebrafish	zgc:92313	ZDB-GENE-040718-339 (Zebrafish Model Organism Database) 436869 (Entrez Gene) zgc:92313 (Alliance of Genome Resources)	Chr12			NP_001002596 (RefSeq) NM_001002596 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.