Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADA	HGNC:186 (HGNC) 100 (Entrez Gene) 608958 (OMIM) ADA (Alliance of Genome Resources)	Chr20 q13.12	Chr20:44584896-44652252 (-) GRCh38	adenosine deaminase deficiency asthma colon cancer pleural tuberculosis severe combined immunodeficiency uterine fibroid	P00813 (UniProt | EBI) NM_001322050 (RefSeq)
mouse	Ada	MGI:87916 (MGI) 11486 (Entrez Gene) Gene Tree Ada (Alliance of Genome Resources)	Chr2 84.44 cM	Chr2:163568504-163592159 (-) GRCm39	adenosine deaminase deficiency	ENSMUSG00000017697 (Ensembl Gene Model) ENSMUSP00000017841 (Ensembl) ENSMUST00000017841 (Ensembl)
rat	Ada	RGD:2031 (Rat Genome Database) 24165 (Entrez Gene) Ada (Alliance of Genome Resources)	Chr3 q42			Q920P6 (UniProt | EBI) NM_130399 (RefSeq)
zebrafish	ada	ZDB-GENE-040718-393 (Zebrafish Model Organism Database) 436919 (Entrez Gene) ada (Alliance of Genome Resources)	Chr23			Q6DG22 (UniProt | EBI) NM_001002646 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.