Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMC6	HGNC:18021 (HGNC) 11322 (Entrez Gene) 605828 (OMIM) TMC6 (Alliance of Genome Resources)	Chr17 q25.3	Chr17:78107397-78132427 (-) GRCh38	epidermodysplasia verruciformis	Q7Z403 (UniProt | EBI) NM_001375354 (RefSeq)
mouse	Tmc6	MGI:1098686 (MGI) 217353 (Entrez Gene) Gene Tree Tmc6 (Alliance of Genome Resources)	Chr11 82.96 cM	Chr11:117656811-117673019 (-) GRCm39		217353 (NCBI Gene Model) Q7TN60 (UniProt | EBI) NM_145439 (RefSeq)
rat	Tmc6	RGD:1591146 (Rat Genome Database) 688280 (Entrez Gene) Tmc6 (Alliance of Genome Resources)	Chr10			NP_001385875 (RefSeq) NM_001398946 (RefSeq)
zebrafish	tmc6b	ZDB-GENE-040718-460 (Zebrafish Model Organism Database) 436978 (Entrez Gene) tmc6b (Alliance of Genome Resources)	Chr11			NP_001002705 (RefSeq) NM_001002705 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.