Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RORC	HGNC:10260 (HGNC) 6097 (Entrez Gene) 602943 (OMIM) RORC (Alliance of Genome Resources)	Chr1 q21.3	Chr1:151806071-151831845 (-) GRCh38	immunodeficiency 42	P51449 (UniProt | EBI) NM_001001523 (RefSeq)
mouse	Rorc	MGI:104856 (MGI) 19885 (Entrez Gene) Gene Tree Rorc (Alliance of Genome Resources)	Chr3 40.56 cM	Chr3:94280106-94305583 (+) GRCm39	Sjogren's syndrome	19885 (NCBI Gene Model) P51450 (UniProt | EBI) NR_121656 (RefSeq)
rat	Rorc	RGD:1595785 (Rat Genome Database) 368158 (Entrez Gene) Rorc (Alliance of Genome Resources)	Chr2 q34			NP_001414201 (RefSeq) NM_001427272 (RefSeq)
zebrafish	rorc	ZDB-GENE-110411-42 (Zebrafish Model Organism Database) 100004847 (Entrez Gene) rorc (Alliance of Genome Resources)	Chr16			XP_001344049 (RefSeq)
	rorca	ZDB-GENE-990415-250 (Zebrafish Model Organism Database) 559245 (Entrez Gene) rorca (Alliance of Genome Resources)	Chr8			NP_001076288 (RefSeq) NM_001082819 (RefSeq)
	rorcb	ZDB-GENE-040724-215 (Zebrafish Model Organism Database) 562258 (Entrez Gene) rorcb (Alliance of Genome Resources)	Chr2			NP_001264023 (RefSeq) NM_001277094 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.