Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ATM	HGNC:795 (HGNC) 472 (Entrez Gene) 607585 (OMIM) ATM (Alliance of Genome Resources)	Chr11 q22.3	Chr11:108222804-108369102 (+) GRCh38	ataxia telangiectasia breast cancer colorectal cancer endometrial cancer female breast cancer lung non-small cell carcinoma lung small cell carcinoma lung squamous cell carcinoma pancreatic cancer papillary thyroid carcinoma Parkinson's disease senile cataract	Q13315 (UniProt | EBI) NM_000051 (RefSeq)
mouse	Atm	MGI:107202 (MGI) 11920 (Entrez Gene) Gene Tree Atm (Alliance of Genome Resources)	Chr9 29.12 cM	Chr9:53350449-53448040 (-) GRCm39	ataxia telangiectasia	ENSMUSG00000034218 (Ensembl Gene Model) ENSMUSP00000156344 (Ensembl) ENSMUST00000232179 (Ensembl)
rat	Atm	RGD:1593265 (Rat Genome Database) 300711 (Entrez Gene) Atm (Alliance of Genome Resources)	Chr8 q24			NP_001100291 (RefSeq) NM_001106821 (RefSeq)
zebrafish	atm	ZDB-GENE-040809-1 (Zebrafish Model Organism Database) 403064 (Entrez Gene) atm (Alliance of Genome Resources)	Chr15			XP_002664603 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.