Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAP3K7	HGNC:6859 (HGNC) 6885 (Entrez Gene) 602614 (OMIM) MAP3K7 (Alliance of Genome Resources)	Chr6 q15	Chr6:90513573-90587086 (-) GRCh38	frontometaphyseal dysplasia frontometaphyseal dysplasia 2 prostate cancer	O43318 (UniProt | EBI) NM_145332 (RefSeq)
mouse	Map3k7	MGI:1346877 (MGI) 26409 (Entrez Gene) Gene Tree Map3k7 (Alliance of Genome Resources)	Chr4 13.91 cM	Chr4:31964097-32023467 (+) GRCm39	Wolff-Parkinson-White syndrome	ENSMUSG00000028284 (Ensembl Gene Model) ENSMUSP00000040307 (Ensembl) ENSMUST00000037607 (Ensembl)
rat	Map3k7	RGD:1309438 (Rat Genome Database) 313121 (Entrez Gene) Map3k7 (Alliance of Genome Resources)	Chr5 q21			P0C8E4 (UniProt | EBI) NM_001107920 (RefSeq)
zebrafish	map3k7	ZDB-GENE-041001-135 (Zebrafish Model Organism Database) 553788 (Entrez Gene) map3k7 (Alliance of Genome Resources)	Chr20			NP_001018586 (RefSeq) NM_001020750 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.