Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HGF	HGNC:4893 (HGNC) 3082 (Entrez Gene) 142409 (OMIM) HGF (Alliance of Genome Resources)	Chr7 q21.11	Chr7:81699010-81770438 (-) GRCh38	angle-closure glaucoma autosomal recessive nonsyndromic deafness 39 bilirubin metabolic disorder diabetic neuropathy graft-versus-host disease hypertension interstitial lung disease keratoconus limb ischemia localized scleroderma myocardial infarction myopia retinal degeneration sciatic neuropathy systemic scleroderma vitiligo	P14210 (UniProt | EBI) NM_000601 (RefSeq)
mouse	Hgf	MGI:96079 (MGI) 15234 (Entrez Gene) Gene Tree Hgf (Alliance of Genome Resources)	Chr5 7.07 cM	Chr5:16758493-16825150 (+) GRCm39	autosomal recessive nonsyndromic deafness 39 breast cancer	ENSMUSG00000028864 (Ensembl Gene Model) ENSMUSP00000030683 (Ensembl) ENSMUST00000030683 (Ensembl)
rat	Hgf	RGD:2794 (Rat Genome Database) 24446 (Entrez Gene) Hgf (Alliance of Genome Resources)	Chr4 q12			P17945 (UniProt | EBI) NM_017017 (RefSeq)
zebrafish	hgfa	ZDB-GENE-041014-2 (Zebrafish Model Organism Database) 493781 (Entrez Gene) hgfa (Alliance of Genome Resources)	Chr4			NP_001013292 (RefSeq) NM_001013274 (RefSeq)
	hgfb	ZDB-GENE-041014-3 (Zebrafish Model Organism Database) 100334116 (Entrez Gene) hgfb (Alliance of Genome Resources)	Chr18			XP_009291749 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.