Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	REG4	HGNC:22977 (HGNC) 83998 (Entrez Gene) 609846 (OMIM) REG4 (Alliance of Genome Resources)	Chr1 p12	Chr1:119794017-119811580 (-) GRCh38		Q9BYZ8 (UniProt | EBI) NM_032044 (RefSeq)
mouse	Reg4	MGI:1914959 (MGI) 67709 (Entrez Gene) Gene Tree Reg4 (Alliance of Genome Resources)	Chr3 42.73 cM	Chr3:98129472-98144064 (+) GRCm39		ENSMUSG00000027876 (Ensembl Gene Model) ENSMUSP00000029469 (Ensembl) ENSMUST00000029469 (Ensembl)
rat	Reg4	RGD:1303341 (Rat Genome Database) 445583 (Entrez Gene) Reg4 (Alliance of Genome Resources)	Chr2 q34			Q68AX7 (UniProt | EBI) NM_001004096 (RefSeq)
zebrafish	si:ch211-125e6.5	ZDB-GENE-070912-39 (Zebrafish Model Organism Database) 100002476 (Entrez Gene) si:ch211-125e6.5 (Alliance of Genome Resources)	Chr9
	si:ch211-125e6.11	ZDB-GENE-070912-35 (Zebrafish Model Organism Database) 100170830 (Entrez Gene) si:ch211-125e6.11 (Alliance of Genome Resources)	Chr9			NP_001124136 (RefSeq) NM_001130664 (RefSeq)
	si:ch211-125e6.14	ZDB-GENE-070912-38 (Zebrafish Model Organism Database) 100002523 (Entrez Gene) si:ch211-125e6.14 (Alliance of Genome Resources)	Chr9			NP_001104711 (RefSeq) NM_001111241 (RefSeq)
	si:dkey-241l7.2	ZDB-GENE-041014-240 (Zebrafish Model Organism Database) 569235 (Entrez Gene) si:dkey-241l7.2 (Alliance of Genome Resources)	Chr20			NP_001231964 (RefSeq) NM_001245035 (RefSeq)
	si:dkey-241l7.3	ZDB-GENE-041014-239 (Zebrafish Model Organism Database) 567766 (Entrez Gene) si:dkey-241l7.3 (Alliance of Genome Resources)	Chr20			XP_005160964 (RefSeq) NM_001245032 (RefSeq)
	si:dkey-241l7.4	ZDB-GENE-041014-238 (Zebrafish Model Organism Database) 100124601 (Entrez Gene) si:dkey-241l7.4 (Alliance of Genome Resources)	Chr20			NP_001352014 (RefSeq) NM_001102628 (RefSeq)
	si:dkey-241l7.5	ZDB-GENE-041014-237 (Zebrafish Model Organism Database) 565442 (Entrez Gene) si:dkey-241l7.5 (Alliance of Genome Resources)	Chr20			NP_001231960 (RefSeq) NM_001245031 (RefSeq)
	si:dkey-241l7.6	ZDB-GENE-041014-235 (Zebrafish Model Organism Database) 567708 (Entrez Gene) si:dkey-241l7.6 (Alliance of Genome Resources)	Chr20			NP_001038606 (RefSeq) NM_001045141 (RefSeq)
	zgc:172053	ZDB-GENE-080219-25 (Zebrafish Model Organism Database) 100002541 (Entrez Gene) zgc:172053 (Alliance of Genome Resources)	Chr9			NP_001104712 (RefSeq) NM_001111242 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.