Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC6A1	HGNC:11042 (HGNC) 6529 (Entrez Gene) 137165 (OMIM) SLC6A1 (Alliance of Genome Resources)	Chr3 p25.3	Chr3:10992186-11039247 (+) GRCh38	alcohol dependence myoclonic-atonic epilepsy	P30531 (UniProt | EBI) NM_001348252 (RefSeq)
mouse	Slc6a1	MGI:95627 (MGI) 232333 (Entrez Gene) Gene Tree Slc6a1 (Alliance of Genome Resources)	Chr6 53.05 cM	Chr6:114259735-114294491 (+) GRCm39	schizophrenia	232333 (NCBI Gene Model) P31648 (UniProt | EBI) NM_178703 (RefSeq)
rat	Slc6a1	RGD:620533 (Rat Genome Database) 79212 (Entrez Gene) Slc6a1 (Alliance of Genome Resources)	Chr4 q42			P23978 (UniProt | EBI) NM_024371 (RefSeq)
zebrafish	slc6a1a	ZDB-GENE-060519-23 (Zebrafish Model Organism Database) 692318 (Entrez Gene) slc6a1a (Alliance of Genome Resources)	Chr23			NP_001038752 (RefSeq) NM_001045287 (RefSeq)
	slc6a1b	ZDB-GENE-041114-57 (Zebrafish Model Organism Database) 492490 (Entrez Gene) slc6a1b (Alliance of Genome Resources)	Chr11			NP_001007363 (RefSeq) NM_001007362 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.