Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PKP2	HGNC:9024 (HGNC) 5318 (Entrez Gene) 602861 (OMIM) PKP2 (Alliance of Genome Resources)	Chr12 p11.21	Chr12:32790745-32896798 (-) GRCh38	arrhythmogenic right ventricular cardiomyopathy arrhythmogenic right ventricular dysplasia 9	Q99959 (UniProt | EBI) NM_001407157 (RefSeq)
mouse	Pkp2	MGI:1914701 (MGI) 67451 (Entrez Gene) Gene Tree Pkp2 (Alliance of Genome Resources)	Chr16 10.09 cM	Chr16:16031209-16090576 (+) GRCm39		67451 (NCBI Gene Model) Q9CQ73 (UniProt | EBI) NM_026163 (RefSeq)
rat	Pkp2	RGD:1306533 (Rat Genome Database) 287925 (Entrez Gene) Pkp2 (Alliance of Genome Resources)	Chr11 q23			F1M7L9 (UniProt | EBI) NM_001100499 (RefSeq)
zebrafish	pkp2	ZDB-GENE-041210-167 (Zebrafish Model Organism Database) 568060 (Entrez Gene) pkp2 (Alliance of Genome Resources)	Chr4			B0BF33 (UniProt | EBI) NM_001113433 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.