Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EXT1	HGNC:3512 (HGNC) 2131 (Entrez Gene) 608177 (OMIM) EXT1 (Alliance of Genome Resources)	Chr8 q24.11	Chr8:117794490-118111826 (-) GRCh38	chondrosarcoma hereditary multiple exostoses	Q16394 (UniProt | EBI) NM_000127 (RefSeq)
mouse	Ext1	MGI:894663 (MGI) 14042 (Entrez Gene) Gene Tree Ext1 (Alliance of Genome Resources)	Chr15 20.0 cM	Chr15:52931657-53209579 (-) GRCm39	autism spectrum disorder hereditary multiple exostoses	14042 (NCBI Gene Model) P97464 (UniProt | EBI) NM_010162 (RefSeq)
rat	Ext1	RGD:1587375 (Rat Genome Database) 299907 (Entrez Gene) Ext1 (Alliance of Genome Resources)	Chr7 q31			NP_001124012 (RefSeq) NM_001130540 (RefSeq)
zebrafish	ext1a	ZDB-GENE-050211-3 (Zebrafish Model Organism Database) 497279 (Entrez Gene) ext1a (Alliance of Genome Resources)	Chr16			Q5IGR8 (UniProt | EBI) NM_001012368 (RefSeq)
	ext1b	ZDB-GENE-050211-4 (Zebrafish Model Organism Database) 497280 (Entrez Gene) ext1b (Alliance of Genome Resources)	Chr19			Q5IGR7 (UniProt | EBI) NM_001012369 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.