Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TCF7	HGNC:11639 (HGNC) 6932 (Entrez Gene) 189908 (OMIM) TCF7 (Alliance of Genome Resources)	Chr5 q31.1	Chr5:134108218-134151865 (+) GRCh38		P36402 (UniProt | EBI) NM_001134852 (RefSeq)
mouse	Tcf7	MGI:98507 (MGI) 21414 (Entrez Gene) Gene Tree Tcf7 (Alliance of Genome Resources)	Chr11 31.86 cM	Chr11:52143198-52174158 (-) GRCm39		ENSMUSG00000000782 (Ensembl Gene Model) ENSMUSP00000104699 (Ensembl) ENSMUST00000109071 (Ensembl)
rat	Tcf7	RGD:1305894 (Rat Genome Database) 363595 (Entrez Gene) Tcf7 (Alliance of Genome Resources)	Chr10 q22			NP_001414359 (RefSeq) NM_001427430 (RefSeq)
zebrafish	tcf7	ZDB-GENE-050222-4 (Zebrafish Model Organism Database) 497649 (Entrez Gene) tcf7 (Alliance of Genome Resources)	Chr21			NP_001012389 (RefSeq) NM_001012389 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.