Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	XPO1	HGNC:12825 (HGNC) 7514 (Entrez Gene) 602559 (OMIM) XPO1 (Alliance of Genome Resources)	Chr2 p15	Chr2:61476032-61538741 (-) GRCh38	colorectal cancer gastric adenocarcinoma hepatocellular carcinoma lung non-small cell carcinoma	O14980 (UniProt | EBI) NM_001410799 (RefSeq)
mouse	Xpo1	MGI:2144013 (MGI) 103573 (Entrez Gene) Gene Tree Xpo1 (Alliance of Genome Resources)	Chr11 14.28 cM	Chr11:23206055-23248249 (+) GRCm39		ENSMUSG00000020290 (Ensembl Gene Model) ENSMUSP00000099934 (Ensembl) ENSMUST00000102870 (Ensembl)
rat	Xpo1	RGD:620517 (Rat Genome Database) 85252 (Entrez Gene) Xpo1 (Alliance of Genome Resources)	Chr14 q22			Q80U96 (UniProt | EBI) NM_053490 (RefSeq)
zebrafish	xpo1a	ZDB-GENE-050309-201 (Zebrafish Model Organism Database) 558395 (Entrez Gene) xpo1a (Alliance of Genome Resources)	Chr1			XP_009292977 (RefSeq)
	xpo1b	ZDB-GENE-070530-6 (Zebrafish Model Organism Database) 561138 (Entrez Gene) xpo1b (Alliance of Genome Resources)	Chr17			XP_009291328 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.