Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NALCN	HGNC:19082 (HGNC) 259232 (Entrez Gene) 611549 (OMIM) NALCN (Alliance of Genome Resources)	Chr13 q32.3-q33.1	Chr13:101053776-101417179 (-) GRCh38	congenital limbs-face contractures-hypotonia-developmental delay syndrome	Q8IZF0 (UniProt | EBI) NM_001350749 (RefSeq)
mouse	Nalcn	MGI:2444306 (MGI) 338370 (Entrez Gene) Gene Tree Nalcn (Alliance of Genome Resources)	Chr14 66.04 cM	Chr14:123514046-123864556 (-) GRCm39		ENSMUSG00000000197 (Ensembl Gene Model) ENSMUSP00000000201 (Ensembl) ENSMUST00000000201 (Ensembl)
rat	Nalcn	RGD:628710 (Rat Genome Database) 266760 (Entrez Gene) Nalcn (Alliance of Genome Resources)	Chr15 q25			Q6Q760 (UniProt | EBI) NM_153630 (RefSeq)
zebrafish	nalcn	ZDB-GENE-050410-12 (Zebrafish Model Organism Database) 548345 (Entrez Gene) nalcn (Alliance of Genome Resources)	Chr9			NP_001017549 (RefSeq) NM_001017549 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.