Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SRD5A2	HGNC:11285 (HGNC) 6716 (Entrez Gene) 607306 (OMIM) SRD5A2 (Alliance of Genome Resources)	Chr2 p23.1	Chr2:31522480-31663009 (-) GRCh38	hypospadias prostate cancer	P31213 (UniProt | EBI) NM_000348 (RefSeq)
mouse	Srd5a2	MGI:2150380 (MGI) 94224 (Entrez Gene) Gene Tree Srd5a2 (Alliance of Genome Resources)	Chr17 45.39 cM	Chr17:74323950-74354911 (-) GRCm39		ENSMUSG00000038541 (Ensembl Gene Model) ENSMUSP00000048862 (Ensembl) ENSMUST00000043458 (Ensembl)
rat	Srd5a2	RGD:621480 (Rat Genome Database) 64677 (Entrez Gene) Srd5a2 (Alliance of Genome Resources)	Chr6 q13			P31214 (UniProt | EBI) NM_022711 (RefSeq)
zebrafish	srd5a2a	ZDB-GENE-050417-199 (Zebrafish Model Organism Database) 550398 (Entrez Gene) srd5a2a (Alliance of Genome Resources)	Chr1			NP_001017703 (RefSeq) NM_001017703 (RefSeq)
	srd5a2b	ZDB-GENE-050417-182 (Zebrafish Model Organism Database) 550388 (Entrez Gene) srd5a2b (Alliance of Genome Resources)	Chr13			NP_001017693 (RefSeq) NM_001431067 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.