Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITPR2	HGNC:6181 (HGNC) 3709 (Entrez Gene) 600144 (OMIM) ITPR2 (Alliance of Genome Resources)	Chr12 p11.23	Chr12:26335352-26833194 (-) GRCh38	amyotrophic lateral sclerosis isolated anhidrosis with normal sweat glands	Q14571 (UniProt | EBI) NM_002223 (RefSeq)
mouse	Itpr2	MGI:99418 (MGI) 16439 (Entrez Gene) Gene Tree Itpr2 (Alliance of Genome Resources)	Chr6 77.7 cM	Chr6:146009797-146403721 (-) GRCm39	isolated anhidrosis with normal sweat glands	ENSMUSG00000030287 (Ensembl Gene Model) ENSMUSP00000049584 (Ensembl) ENSMUST00000053273 (Ensembl)
rat	Itpr2	RGD:69649 (Rat Genome Database) 81678 (Entrez Gene) Itpr2 (Alliance of Genome Resources)	Chr4 q44			P29995 (UniProt | EBI) NM_031046 (RefSeq)
zebrafish	itpr2	ZDB-GENE-050419-192 (Zebrafish Model Organism Database) 562585 (Entrez Gene) itpr2 (Alliance of Genome Resources)	Chr18			XP_021323455 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.