Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IGHMBP2	HGNC:5542 (HGNC) 3508 (Entrez Gene) 600502 (OMIM) IGHMBP2 (Alliance of Genome Resources)	Chr11 q13.3	Chr11:68903863-68940602 (+) GRCh38	autosomal recessive distal hereditary motor neuronopathy 1 Charcot-Marie-Tooth disease axonal type 2S	P38935 (UniProt | EBI) NM_002180 (RefSeq)
mouse	Ighmbp2	MGI:99954 (MGI) 20589 (Entrez Gene) Gene Tree Ighmbp2 (Alliance of Genome Resources)	Chr19 3.03 cM	Chr19:3309076-3333011 (-) GRCm39	autosomal recessive distal hereditary motor neuronopathy 1 Charcot-Marie-Tooth disease axonal type 2S	20589 (NCBI Gene Model) P40694 (UniProt | EBI) NM_009212 (RefSeq)
rat	Ighmbp2	RGD:68325 (Rat Genome Database) 29532 (Entrez Gene) Ighmbp2 (Alliance of Genome Resources)	Chr1 q42			Q9EQN5 (UniProt | EBI) NM_031586 (RefSeq)
zebrafish	ighmbp2	ZDB-GENE-050419-258 (Zebrafish Model Organism Database) 556484 (Entrez Gene) ighmbp2 (Alliance of Genome Resources)	Chr18			NP_001038365 (RefSeq) NM_001044900 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.