Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	INPP5E	HGNC:21474 (HGNC) 56623 (Entrez Gene) 613037 (OMIM) INPP5E (Alliance of Genome Resources)	Chr9 q34.3	Chr9:136428619-136439845 (-) GRCh38	Joubert syndrome Joubert syndrome 1	Q9NRR6 (UniProt | EBI) NM_001318502 (RefSeq)
mouse	Inpp5e	MGI:1927753 (MGI) 64436 (Entrez Gene) Gene Tree Inpp5e (Alliance of Genome Resources)	Chr2 18.88 cM	Chr2:26286261-26299215 (-) GRCm39		ENSMUSG00000026925 (Ensembl Gene Model) ENSMUSP00000119485 (Ensembl) ENSMUST00000145701 (Ensembl)
rat	Inpp5e	RGD:620478 (Rat Genome Database) 114089 (Entrez Gene) Inpp5e (Alliance of Genome Resources)	Chr3 p13			Q9WVR1 (UniProt | EBI) NM_053632 (RefSeq)
zebrafish	inpp5e	ZDB-GENE-050809-23 (Zebrafish Model Organism Database) 606579 (Entrez Gene) inpp5e (Alliance of Genome Resources)	Chr5			NP_001096089 (RefSeq) NM_001102619 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.