Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RAB27A	HGNC:9766 (HGNC) 5873 (Entrez Gene) 603868 (OMIM) RAB27A (Alliance of Genome Resources)	Chr15 q21.3	Chr15:55202966-55319113 (-) GRCh38	Griscelli syndrome type 2 non-Langerhans-cell histiocytosis	P51159 (UniProt | EBI) NM_183234 (RefSeq)
mouse	Rab27a	MGI:1861441 (MGI) 11891 (Entrez Gene) Gene Tree Rab27a (Alliance of Genome Resources)	Chr9 40.08 cM	Chr9:72952136-73004911 (+) GRCm39	hemophagocytic lymphohistiocytosis Hermansky-Pudlak syndrome 1 platelet storage pool deficiency	ENSMUSG00000032202 (Ensembl Gene Model) ENSMUSP00000139310 (Ensembl) ENSMUST00000184146 (Ensembl)
rat	Rab27a	RGD:620918 (Rat Genome Database) 50645 (Entrez Gene) Rab27a (Alliance of Genome Resources)	Chr8 q24			P23640 (UniProt | EBI) NM_017317 (RefSeq)
zebrafish	rab27a	ZDB-GENE-050913-46 (Zebrafish Model Organism Database) 570907 (Entrez Gene) rab27a (Alliance of Genome Resources)	Chr18			NP_001025428 (RefSeq) NM_001030257 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.