Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IRAK3	HGNC:17020 (HGNC) 11213 (Entrez Gene) 604459 (OMIM) IRAK3 (Alliance of Genome Resources)	Chr12 q14.3	Chr12:66189195-66254622 (+) GRCh38	asthma	Q9Y616 (UniProt | EBI) NM_001142523 (RefSeq)
mouse	Irak3	MGI:1921164 (MGI) 73914 (Entrez Gene) Gene Tree Irak3 (Alliance of Genome Resources)	Chr10 67.94 cM	Chr10:119977553-120038035 (-) GRCm39	osteoporosis type 1 diabetes mellitus	73914 (NCBI Gene Model) Q8K4B2 (UniProt | EBI) NR_152856 (RefSeq)
rat	Irak3	RGD:1308846 (Rat Genome Database) 314870 (Entrez Gene) Irak3 (Alliance of Genome Resources)	Chr7 q22			NP_001101571 (RefSeq) NM_001108101 (RefSeq)
zebrafish	irak3	ZDB-GENE-060503-710 (Zebrafish Model Organism Database) 567444 (Entrez Gene) irak3 (Alliance of Genome Resources)	Chr4			XP_017210784 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.