Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CNTF	HGNC:2169 (HGNC) 1270 (Entrez Gene) 118945 (OMIM) CNTF (Alliance of Genome Resources)	Chr11 q12.1	Chr11:58622665-58625733 (+) GRCh38	disease of mental health glaucoma Huntington's disease multiple sclerosis obesity	P26441 (UniProt | EBI) NM_000614 (RefSeq)
mouse	Cntf	MGI:88439 (MGI) 12803 (Entrez Gene) Gene Tree Cntf (Alliance of Genome Resources)	Chr19 8.73 cM	Chr19:12741024-12742996 (-) GRCm39		ENSMUSG00000079415 (Ensembl Gene Model) ENSMUSP00000108555 (Ensembl) ENSMUST00000112933 (Ensembl)
rat	Cntf	RGD:2370 (Rat Genome Database) 25707 (Entrez Gene) Cntf (Alliance of Genome Resources)	Chr1 q43			P20294 (UniProt | EBI) NM_013166 (RefSeq)
zebrafish	m17	ZDB-GENE-060526-368 (Zebrafish Model Organism Database) 555717 (Entrez Gene) m17 (Alliance of Genome Resources)	Chr5			NP_001073302 (RefSeq) NM_001079833 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.