Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNB1	HGNC:1961 (HGNC) 1140 (Entrez Gene) 100710 (OMIM) CHRNB1 (Alliance of Genome Resources)	Chr17 p13.1	Chr17:7445061-7457710 (+) GRCh38	congenital myasthenic syndrome 2A congenital myasthenic syndrome 2C	P11230 (UniProt | EBI) NM_000747 (RefSeq)
mouse	Chrnb1	MGI:87890 (MGI) 11443 (Entrez Gene) Gene Tree Chrnb1 (Alliance of Genome Resources)	Chr11 42.87 cM	Chr11:69674862-69686742 (-) GRCm39		11443 (NCBI Gene Model) P09690 (UniProt | EBI) NM_009601 (RefSeq)
rat	Chrnb1	RGD:2349 (Rat Genome Database) 24261 (Entrez Gene) Chrnb1 (Alliance of Genome Resources)	Chr10 q24			P25109 (UniProt | EBI) NM_001429879 (RefSeq)
zebrafish	chrnb1	ZDB-GENE-070821-4 (Zebrafish Model Organism Database) 100006941 (Entrez Gene) chrnb1 (Alliance of Genome Resources)	Chr7			NP_001240739 (RefSeq) NM_001253810 (RefSeq)
	chrnb1l	ZDB-GENE-060811-1 (Zebrafish Model Organism Database) 100005295 (Entrez Gene) chrnb1l (Alliance of Genome Resources)	Chr7			NP_001233249 (RefSeq) NM_001246320 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.