Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRKAG2	HGNC:9386 (HGNC) 51422 (Entrez Gene) 602743 (OMIM) PRKAG2 (Alliance of Genome Resources)	Chr7 q36.1	Chr7:151556124-151877214 (-) GRCh38	glycogen storage disease hypertrophic cardiomyopathy 6 lethal congenital glycogen storage disease of heart Wolff-Parkinson-White syndrome	Q9UGJ0 (UniProt | EBI) NM_001363698 (RefSeq)
mouse	Prkag2	MGI:1336153 (MGI) 108099 (Entrez Gene) Gene Tree Prkag2 (Alliance of Genome Resources)	Chr5 11.93 cM	Chr5:25067742-25305640 (-) GRCm39		ENSMUSG00000028944 (Ensembl Gene Model) ENSMUSP00000030784 (Ensembl) ENSMUST00000030784 (Ensembl)
rat	Prkag2	RGD:727782 (Rat Genome Database) 373545 (Entrez Gene) Prkag2 (Alliance of Genome Resources)	Chr4 q11			NP_001385808 (RefSeq) NM_184051 (RefSeq)
zebrafish	prkag2a	ZDB-GENE-060929-160 (Zebrafish Model Organism Database) 570761 (Entrez Gene) prkag2a (Alliance of Genome Resources)	Chr24			NP_001315359 (RefSeq) NM_001328430 (RefSeq)
	prkag2b	ZDB-GENE-070912-442 (Zebrafish Model Organism Database) 568316 (Entrez Gene) prkag2b (Alliance of Genome Resources)	Chr2			XP_005163357 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.