Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMPD3	HGNC:14240 (HGNC) 55512 (Entrez Gene) 605777 (OMIM) SMPD3 (Alliance of Genome Resources)	Chr16 q22.1	Chr16:68358327-68448508 (-) GRCh38		Q9NY59 (UniProt | EBI) NM_018667 (RefSeq)
mouse	Smpd3	MGI:1927578 (MGI) 58994 (Entrez Gene) Gene Tree Smpd3 (Alliance of Genome Resources)	Chr8 53.12 cM	Chr8:106979180-107064597 (-) GRCm39	hypopituitarism osteogenesis imperfecta osteogenesis imperfecta type 2 osteogenesis imperfecta type 3	58994 (NCBI Gene Model) Q9JJY3 (UniProt | EBI) NM_021491 (RefSeq)
rat	Smpd3	RGD:619754 (Rat Genome Database) 94338 (Entrez Gene) Smpd3 (Alliance of Genome Resources)	Chr19 q12			O35049 (UniProt | EBI) NM_053605 (RefSeq)
zebrafish	smpd3	ZDB-GENE-081104-280 (Zebrafish Model Organism Database) 568381 (Entrez Gene) smpd3 (Alliance of Genome Resources)	Chr25			NP_001116222 (RefSeq) NM_001122750 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.