Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MET	HGNC:7029 (HGNC) 4233 (Entrez Gene) 164860 (OMIM) MET (Alliance of Genome Resources)	Chr7 q31.2	Chr7:116672196-116798377 (+) GRCh38	autistic disorder autosomal recessive nonsyndromic deafness 97 distal arthrogryposis hepatocellular carcinoma large cell carcinoma multiple myeloma papillary renal cell carcinoma renal cell carcinoma	P08581 (UniProt | EBI) NM_001127500 (RefSeq)
mouse	Met	MGI:96969 (MGI) 17295 (Entrez Gene) Gene Tree Met (Alliance of Genome Resources)	Chr6 7.83 cM	Chr6:17463799-17573979 (+) GRCm39	autism spectrum disorder breast cancer gestational diabetes Gilles de la Tourette syndrome	ENSMUSG00000009376 (Ensembl Gene Model) ENSMUSP00000111103 (Ensembl) ENSMUST00000115443 (Ensembl)
rat	Met	RGD:3082 (Rat Genome Database) 24553 (Entrez Gene) Met (Alliance of Genome Resources)	Chr4 q22			P97523 (UniProt | EBI) NM_031517 (RefSeq)
zebrafish	met	ZDB-GENE-041014-1 (Zebrafish Model Organism Database) 100150664 (Entrez Gene) met (Alliance of Genome Resources)	Chr25			NP_001007125 (RefSeq) NM_001007124 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.