Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KDM6A	HGNC:12637 (HGNC) 7403 (Entrez Gene) 300128 (OMIM) KDM6A (Alliance of Genome Resources)	ChrX p11.3	ChrX:44873188-45112779 (+) GRCh38	acute lymphoblastic leukemia adenoid cystic carcinoma bladder urothelial carcinoma colon adenocarcinoma colorectal cancer esophagus squamous cell carcinoma hepatocellular carcinoma Kabuki syndrome lung non-small cell carcinoma lung small cell carcinoma stomach cancer triple-receptor negative breast cancer	O15550 (UniProt | EBI) NM_001419810 (RefSeq)
mouse	Kdm6a	MGI:1095419 (MGI) 22289 (Entrez Gene) Gene Tree Kdm6a (Alliance of Genome Resources)	ChrX 13.45 cM	ChrX:18028814-18146175 (+) GRCm39	chronic myelomonocytic leukemia	ENSMUSG00000037369 (Ensembl Gene Model) ENSMUSP00000061539 (Ensembl) ENSMUST00000052368 (Ensembl)
rat	Kdm6a	RGD:9275041 (Rat Genome Database) 103689969 (Entrez Gene) Kdm6a (Alliance of Genome Resources)	ChrX			NP_001414526 (RefSeq) NM_001427597 (RefSeq)
zebrafish	kdm6a	ZDB-GENE-081105-56 (Zebrafish Model Organism Database) 569277 (Entrez Gene) kdm6a (Alliance of Genome Resources)	Chr9			XP_005167852 (RefSeq)
	kdm6al	ZDB-GENE-070112-2002 (Zebrafish Model Organism Database) 569207 (Entrez Gene) kdm6al (Alliance of Genome Resources)	Chr6			NP_001073662 (RefSeq) NM_001080193 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.