Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	THEM4	HGNC:17947 (HGNC) 117145 (Entrez Gene) 606388 (OMIM) THEM4 (Alliance of Genome Resources)	Chr1 q21.3	Chr1:151870866-151909637 (-) GRCh38		Q5T1C6 (UniProt | EBI) NM_053055 (RefSeq)
mouse	Them4	MGI:1923028 (MGI) 75778 (Entrez Gene) Gene Tree Them4 (Alliance of Genome Resources)	Chr3 40.51 cM	Chr3:94217415-94239847 (+) GRCm39		75778 (NCBI Gene Model) Q3UUI3 (UniProt | EBI) NM_029431 (RefSeq)
rat	Them4	RGD:1304723 (Rat Genome Database) 361992 (Entrez Gene) Them4 (Alliance of Genome Resources)	Chr2 q34			Q566R0 (UniProt | EBI) NM_001025017 (RefSeq)
zebrafish	them4	ZDB-GENE-070112-982 (Zebrafish Model Organism Database) 791152 (Entrez Gene) them4 (Alliance of Genome Resources)	Chr16			NP_001074103 (RefSeq) NM_001080634 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.