Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SREBF2	HGNC:11290 (HGNC) 6721 (Entrez Gene) 600481 (OMIM) SREBF2 (Alliance of Genome Resources)	Chr22 q13.2	Chr22:41833105-41907306 (+) GRCh38	carotid artery disease prostate cancer sarcoma type 1 diabetes mellitus type 2 diabetes mellitus vascular dementia	Q12772 (UniProt | EBI) NM_004599 (RefSeq)
mouse	Srebf2	MGI:107585 (MGI) 20788 (Entrez Gene) Gene Tree Srebf2 (Alliance of Genome Resources)	Chr15 38.49 cM	Chr15:82031455-82089580 (+) GRCm39		20788 (NCBI Gene Model) Q3U1N2 (UniProt | EBI) NM_001411792 (RefSeq)
rat	Srebf2	RGD:1307751 (Rat Genome Database) 300095 (Entrez Gene) Srebf2 (Alliance of Genome Resources)	Chr7 q34			Q3T1I5 (UniProt | EBI) NM_001033694 (RefSeq)
zebrafish	srebf2	ZDB-GENE-070410-8 (Zebrafish Model Organism Database) 100037309 (Entrez Gene) srebf2 (Alliance of Genome Resources)	Chr3			A3KNA7 (UniProt | EBI) NM_001089466 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.