Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP11B1	HGNC:2591 (HGNC) 1584 (Entrez Gene) 610613 (OMIM) CYP11B1 (Alliance of Genome Resources)	Chr8 q24.3	Chr8:142872356-142879846 (-) GRCh38	congenital adrenal hyperplasia glucocorticoid-remediable aldosteronism primary hyperaldosteronism	P15538 (UniProt | EBI) NM_001026213 (RefSeq)
	CYP11B2	HGNC:2592 (HGNC) 1585 (Entrez Gene) 124080 (OMIM) CYP11B2 (Alliance of Genome Resources)	Chr8 q24.3	Chr8:142910559-142917843 (-) GRCh38	corticosterone methyloxidase deficiency 1 diabetes mellitus dilated cardiomyopathy 1H hypertension pre-eclampsia primary hyperaldosteronism type 2 diabetes mellitus	P19099 (UniProt | EBI) NM_000498 (RefSeq)
mouse	Cyp11b2	MGI:88584 (MGI) 13072 (Entrez Gene) Gene Tree Cyp11b2 (Alliance of Genome Resources)	Chr15 34.29 cM	Chr15:74722859-74728167 (-) GRCm39		ENSMUSG00000022589 (Ensembl Gene Model) ENSMUSP00000131503 (Ensembl) ENSMUST00000167634 (Ensembl)
rat	Cyp11b2	RGD:2454 (Rat Genome Database) 24294 (Entrez Gene) Cyp11b2 (Alliance of Genome Resources)	Chr7 q34			P30099 (UniProt | EBI) NM_012538 (RefSeq)
	Cyp11b3	RGD:727886 (Rat Genome Database) 353498 (Entrez Gene) Cyp11b3 (Alliance of Genome Resources)	Chr7 q34			NP_861545 (RefSeq) NM_181824 (RefSeq)
zebrafish	cyp11c1	ZDB-GENE-070828-1 (Zebrafish Model Organism Database) 791124 (Entrez Gene) cyp11c1 (Alliance of Genome Resources)	Chr16			NP_001073673 (RefSeq) NM_001080204 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.