Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AGTR1	HGNC:336 (HGNC) 185 (Entrez Gene) 106165 (OMIM) AGTR1 (Alliance of Genome Resources)	Chr3 q24	Chr3:148697784-148743008 (+) GRCh38	Alzheimer's disease breast cancer carotid artery disease cerebrovascular disease chronic kidney disease coronary artery disease COVID-19 essential hypertension Friedreich ataxia hypertension myocardial infarction pulmonary hypertension sarcoidosis	P30556 (UniProt | EBI) NM_031850 (RefSeq)
mouse	Agtr1a	MGI:87964 (MGI) 11607 (Entrez Gene) Gene Tree Agtr1a (Alliance of Genome Resources)	Chr13 13.19 cM	Chr13:30520424-30566850 (+) GRCm39		ENSMUSG00000049115 (Ensembl Gene Model) ENSMUSP00000070958 (Ensembl) ENSMUST00000066412 (Ensembl)
rat	Agtr1a	RGD:2070 (Rat Genome Database) 24180 (Entrez Gene) Agtr1a (Alliance of Genome Resources)	Chr17 p12			P25095 (UniProt | EBI) NM_030985 (RefSeq)
zebrafish	agtr1a	ZDB-GENE-070912-546 (Zebrafish Model Organism Database) 794575 (Entrez Gene) agtr1a (Alliance of Genome Resources)	Chr2			XP_017207174 (RefSeq)
	agtr1b	ZDB-GENE-110411-117 (Zebrafish Model Organism Database) 100333455 (Entrez Gene) agtr1b (Alliance of Genome Resources)	Chr24			XP_005162585 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.